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p38α MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure

The p38α mitogen-activated protein kinase (MAPK) has been related to gluconeogenesis and lipid metabolism. However, the roles and related mechanisms of p38α MAPK in intestinal failure (IF)-associated liver steatosis remained poor understood. Here, our experimental evidence suggested that p38α MAPK s...

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Detalles Bibliográficos
Autores principales: Xiao, Yongtao, Wang, Jun, Yan, Weihui, Zhou, Kejun, Cao, Yi, Cai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682685/
https://www.ncbi.nlm.nih.gov/pubmed/29022907
http://dx.doi.org/10.1038/cddis.2017.523