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Primary hypothyroidism and isolated ACTH deficiency induced by nivolumab therapy: Case report and review

RATIONALE: Nivolumab is a monoclonal IgG antibody blocking programmed death receptor-1 (PD1), leading to restoration of the natural T-cell-mediated immune response against the cancer cells. However, it also causes plenty of autoimmune-related adverse events, which often involves endocrine system. PA...

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Detalles Bibliográficos
Autores principales: Zeng, Mei Fang, Chen, Li, Ye, Hong Ying, Gong, Wei, Zhou, Li Nuo, Li, Yi Ming, Zhao, Xiao Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682799/
https://www.ncbi.nlm.nih.gov/pubmed/29095280
http://dx.doi.org/10.1097/MD.0000000000008426