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Primary hypothyroidism and isolated ACTH deficiency induced by nivolumab therapy: Case report and review
RATIONALE: Nivolumab is a monoclonal IgG antibody blocking programmed death receptor-1 (PD1), leading to restoration of the natural T-cell-mediated immune response against the cancer cells. However, it also causes plenty of autoimmune-related adverse events, which often involves endocrine system. PA...
Autores principales: | Zeng, Mei Fang, Chen, Li, Ye, Hong Ying, Gong, Wei, Zhou, Li Nuo, Li, Yi Ming, Zhao, Xiao Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682799/ https://www.ncbi.nlm.nih.gov/pubmed/29095280 http://dx.doi.org/10.1097/MD.0000000000008426 |
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