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Knockdown of SOX2OT inhibits the malignant biological behaviors of glioblastoma stem cells via up-regulating the expression of miR-194-5p and miR-122

BACKGROUND: Accumulating evidence has highlighted the potential role of long non-coding RNAs (lncRNAs) in the biological behaviors of glioblastoma stem cells (GSCs). Here, we elucidated the function and possible molecular mechanisms of the effect of lncRNA-SOX2OT on the biological behaviors of GSCs....

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Detalles Bibliográficos
Autores principales: Su, Rui, Cao, Shuo, Ma, Jun, Liu, Yunhui, Liu, Xiaobai, Zheng, Jian, Chen, Jiajia, Liu, Libo, Cai, Heng, Li, Zhen, Zhao, Lini, He, Qianru, Xue, Yixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683208/
https://www.ncbi.nlm.nih.gov/pubmed/29132362
http://dx.doi.org/10.1186/s12943-017-0737-1