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Germacranolide-type sesquiterpene lactones from Smallanthus sonchifolius with promising activity against Leishmania mexicana and Trypanosoma cruzi

BACKGROUND: Leishmaniasis and Chagas disease are life-threatening illnesses caused by the protozoan parasites Leishmania spp. and Trypanosoma cruzi, respectively. They are known as “neglected diseases” due to the lack of effective drug treatments and the scarcity of research work devoted to them. Th...

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Detalles Bibliográficos
Autores principales: Ulloa, Jerónimo L., Spina, Renata, Casasco, Agustina, Petray, Patricia B., Martino, Virginia, Sosa, Miguel A., Frank, Fernanda M., Muschietti, Liliana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683217/
https://www.ncbi.nlm.nih.gov/pubmed/29132413
http://dx.doi.org/10.1186/s13071-017-2509-6