AC-93253 iodide, a novel Src inhibitor, suppresses NSCLC progression by modulating multiple Src-related signaling pathways

BACKGROUND: The tyrosine kinase Src is involved in the progression of many cancers. Moreover, inhibiting Src activity has been shown to obstruct several signaling pathways regulated by the EGFR. Thus, Src is a valuable target molecule in drug development. The purpose of this study was to identify co...

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Detalles Bibliográficos
Autores principales: Lai, Yi-Hua, Lin, Sih-Yin, Wu, Yu-Shan, Chen, Huei-Wen, Chen, Jeremy J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683468/
https://www.ncbi.nlm.nih.gov/pubmed/29132432
http://dx.doi.org/10.1186/s13045-017-0539-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683468/
https://www.ncbi.nlm.nih.gov/pubmed/29132432
http://dx.doi.org/10.1186/s13045-017-0539-3

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