Cargando…

A new approach to alkaloid-like systems: synthesis and crystal structure of 1-(2-acetyl-11-methoxy-5,6-dihydro[1,3]dioxolo[4,5-g]pyrrolo[2,1-a]isoquinolin-1-yl)propan-2-one

The title compound, C(19)H(19)NO(5), (I), is the product of a domino reaction between cotarnine chloride and acetylacetylene catalysed by copper(I) iodide. The molecule of (I) comprises a fused tetracyclic system containing two terminal five-membered rings (pyrrole and 1,3-dioxole) and two centra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anh, Le Tuan, Titov, Alexander A., Samavati, Reza, Voskressensky, Leonid G., Varlamov, Alexey V., Khrustalev, Victor N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2017
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683501/ https://www.ncbi.nlm.nih.gov/pubmed/29152361 http://dx.doi.org/10.1107/S2056989017015110

Ejemplares similares

Ethyl 2-phenyl-5,6-dihydropyrrolo[2,1-a]isoquinoline-3-carboxylate
por: Yu, Zhao-Peng, et al.
Publicado: (2012)

8H-Chromeno[2′,3′:4,5]imidazo[2,1-a]isoquinoline
por: Safarov, Saifidin, et al.
Publicado: (2010)

2-(3-Chloro-5,6-diphenyl-2,5-dihydro-1,2,4-triazin-5-yl)-2-methylpropanenitrile
por: Wolińska, Ewa, et al.
Publicado: (2012)

7-Pivaloyl-5,6-dihydro-4H-naphtho[3,2,1-de]isoquinoline-4,6-dione
por: Yu, Hai-Tao, et al.
Publicado: (2010)

Multicomponent Reaction for the Synthesis of 5,6-Dihydropyrrolo[2,1-a]isoquinolines
por: Ghosh, Aritra, et al.
Publicado: (2019)

7-Chloro-1,2-dihydrofuro[2,3-c]isoquinolin-5-amine
por: Okuda, Kensuke, et al.
Publicado: (2010)

Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition
por: Dumitrascu, Florea, et al.
Publicado: (2013)

6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole
por: Morales-Collazo, Oscar, et al.
Publicado: (2020)

Synthesis, solvatochromism and crystal structure of 5-Methoxy-5,6-diphenyl-4,5-dihydro-2H −1,2,4-triazine-3-thione
por: Rezaei, Behrooz, et al.
Publicado: (2013)

Phenyl(pyrrolo[2,1-a]isoquinolin-3-yl)methanone
por: Liu, Yun, et al.
Publicado: (2010)

(6S*)-6-[(1S*,2R*)-1,2-Dihydroxypentyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
por: Valenti, Domenic J., et al.
Publicado: (2013)

Dimethyl 3-(cyclopropylcarbonyl)pyrrolo[2,1-a]isoquinoline-1,2-dicarboxylate
por: Xing, Honglong, et al.
Publicado: (2012)

10′-Chloro-3′,4′-dihydro-2′H-spiro[cyclopropane-1,7′(6′H)-pyrimido[2,1-a]isoquinolin]-6′-one
por: Okuda, Kensuke, et al.
Publicado: (2012)

(3R*,5′S*)-6,7-Dimethoxy-3-(4′-methoxy-6′-methyl-5′,6′,7′,8′-tetrahydro-1,3-dioxolo[4,5-g]isoquinolin-5′-yl)isobenzofuran-1(3H)-one (racemic α-noscapine)
por: von Langermann, Jan, et al.
Publicado: (2010)

2,3-Dihydropyrrolo[2,1-b]quinazoline-9(1H)-thione
por: Nasrullayev, Azizbek O., et al.
Publicado: (2012)

2,3-Dihydro-1H-pyrrolo[1,2-a]indole-9-carbonitrile
por: Madeley, Lee G., et al.
Publicado: (2012)

5-Phenyl-7,8-dihydro-1,3-dioxano[4,5-g]isoquinoline
por: Li, Jiu-Ming, et al.
Publicado: (2008)

Design and Synthesis of Pyrrolo[2,1-a]Isoquinoline-Based Derivatives as New Cytotoxic Agents
por: Kakhki, Samaneh, et al.
Publicado: (2016)

5,6-Dihydro-2H-1,3-dithiolo[4,5-b][1,4]dioxine-2-thione
por: Wang, Guan-nan, et al.
Publicado: (2011)

2-(4-Methoxyphenyl)-4,5-dihydro-1H-imidazole
por: Kia, Reza, et al.
Publicado: (2009)

2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol
por: Eltayeb, Naser Eltaher, et al.
Publicado: (2011)

Ethyl 1-(4-methoxyphenyl)-2-nitro-3-[4-oxo-3-phenyl-1-(4-methoxyphenyl)azetidin-2-yl]-2,3,10,10a-tetrahydro-1H,5H-pyrrolo[1,2-b]isoquinoline-10a-carboxylate
por: Kamala, E. Theboral Sugi, et al.
Publicado: (2008)

2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methylphenol
por: Eltayeb, Naser Eltaher, et al.
Publicado: (2011)

7-(Benzylsulfanyl)-5-(2-methoxyphenyl)-1,3-dimethyl-5,6-dihydropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione
por: Bazgir, Ayoob, et al.
Publicado: (2008)

Unusual thermolysis of azacyclic allene under microwave conditions: crystal structure of (3RS,3aSR,8RS,8aRS)-methyl 5,6-dimethoxy-3a,10-dimethyl-1-phenyl-3,3a,8,8a-tetrahydro-3,8-(epiminomethano)cyclopenta[a]indene-2-carboxylate from synchrotron X-ray diffraction
por: Anh, Le Tuan, et al.
Publicado: (2017)

Acid-Promoted Redox-Annulation toward 1,2-Disubstituted-5,6-dihydropyrrolo[2,1-α]isoquinolines: Synthesis of the Lamellarin Core
por: Hou, Guo-Quan, et al.
Publicado: (2022)

3-Methyl-1,2,3,4,5,6,1′,2′,3′,4′-decahydrospiro[benz[f]isoquinoline-1,2′-naphthalen]-1′-one
por: Siaka, Sohro, et al.
Publicado: (2012)

2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol
por: Eltayeb, Naser Eltaher, et al.
Publicado: (2011)

6-(2-Fluorophenyl)-5,6-dihydrobenzimidazolo[1,2-c]quinazoline
por: Li, Ai-Ke, et al.
Publicado: (2008)

1-{3-(4-Chlorophenyl)-5-[4-(propan-2-yl)phenyl]-4,5-dihydro-1H-pyrazol-1-yl}propan-1-one
por: Narayana, B., et al.
Publicado: (2014)

5,6-Dichloro-2-(3-methoxyphenyl)isoindoline-1,3-dione
por: Büyükgüngör, Orhan, et al.
Publicado: (2008)

(R)-4-Phenyl-2-[(S)-1,2,3,4-tetrahydroisoquinolin-3-yl]-4,5-dihydro-1,3-oxazole
por: Chakka, Sai K., et al.
Publicado: (2010)

Ethyl 3-[1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2-yl]-2-nitro-1-phenyl-2,3,10,10a-tetrahydro-1H,5H-pyrrolo[1,2-b]isoquinoline-10a-carboxylate
por: Sundaresan, S. S., et al.
Publicado: (2010)

Eco-compatible sonochemical synthesis of 8-aryl-7,8-dihydro-[1,3]-dioxolo[4,5-g]quinolin-6(5H)-ones using green TiO(2)
por: Bhardwaj, Diksha, et al.
Publicado: (2019)

(3S,7aR)-7-Methoxy-7a-methyl-3-phenyl-2,3-dihydropyrrolo[2,1-b]oxazol-5(7aH)-one
por: Zheng, Jian-Feng, et al.
Publicado: (2008)

2-(2-Methoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole
por: Thiruvalluvar, A., et al.
Publicado: (2007)

5-(4-Chlorophenyl)-6-isopropyl-5,6-dihydro-4H-pyrrolo[3,4-c]isoxazole
por: Ha, Kwang, et al.
Publicado: (2010)

2-Methyl-1,1-diphenyl-2-[(4S)-4-phenyl-4,5-dihydro-1,3-oxazol-2-yl]propan-1-ol
por: Jia, Wen-Xiao, et al.
Publicado: (2013)

5-(4-Methylphenyl)-2,3-diphenyl-5,6-dihydroimidazo[1,2-c]quinazoline
por: Zhang, Jiankang, et al.
Publicado: (2010)

(Phenyl)(3-phenylsulfonyl-1,2-dihydropyrrolo[1,2-a]quinoxalin-1-yl)methanone
por: Dürüst, Yaşar, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_5l514jlcuvg01un0nflg8fpcme