The Role of Protein Kinase B Signaling Pathway in Anti-Cancer Effect of Rolipram on Glioblastoma Multiforme: An In Vitro Study

INTRODUCTION: The mechanism of putative cytotoxicity of 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidone (rolipram), a specific phosphodiesterase-4 (PDE4) inhibitor, on glioblastoma multiforme (GBM) is almost unknown. This study aimed to investigate the role of protein kinase B (Akt) pathway in...

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Detalles Bibliográficos
Autores principales: Ramezani, Sara, Hadjighassem, Mahmoudreza, Vousooghi, Nasim, Parvaresh, Mansour, Arbabi, Farshid, Amini, Naser, Joghataei, Mohammad Taghi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neuroscience Society 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683690/
https://www.ncbi.nlm.nih.gov/pubmed/29158883
http://dx.doi.org/10.18869/nirp.bcn.8.4.325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683690/
https://www.ncbi.nlm.nih.gov/pubmed/29158883
http://dx.doi.org/10.18869/nirp.bcn.8.4.325

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