Cargando…

Shortened Penetratin Cell-Penetrating Peptide Is Insufficient for Cytosolic Delivery of a Grb7 Targeting Peptide

[Image: see text] Delivery across the cell membrane is of critical importance for the development of therapeutics targeting intracellular proteins. The use of cell-penetrating peptides (CPPs), such as Penetratin (P16), has facilitated the delivery of otherwise cell-impermeable molecules allowing the...

Descripción completa

Detalles Bibliográficos
Autores principales: Watson, Gabrielle M., Kulkarni, Ketav, Brandt, Rebecca, Del Borgo, Mark P., Aguilar, Marie-Isabel, Wilce, Jacqueline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683694/
https://www.ncbi.nlm.nih.gov/pubmed/29152602
http://dx.doi.org/10.1021/acsomega.6b00561