Nck deficiency is associated with delayed breast carcinoma progression and reduced metastasis

Although it is known that noncatalytic region of tyrosine kinase (Nck) regulates cell adhesion and migration by bridging tyrosine phosphorylation with cytoskeletal remodeling, the role of Nck in tumorigenesis and metastasis has remained undetermined. Here we report that Nck is required for the growt...

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Detalles Bibliográficos
Autores principales: Morris, David C., Popp, Julia L., Tang, Leung K., Gibbs, Holly C., Schmitt, Emily, Chaki, Sankar P., Bywaters, Briana C., Yeh, Alvin T., Porter, Weston W., Burghardt, Robert C., Barhoumi, Rola, Rivera, Gonzalo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683761/
https://www.ncbi.nlm.nih.gov/pubmed/28954862
http://dx.doi.org/10.1091/mbc.E17-02-0106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683761/
https://www.ncbi.nlm.nih.gov/pubmed/28954862
http://dx.doi.org/10.1091/mbc.E17-02-0106

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