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Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2

Eph receptor tyrosine kinases and their ephrin ligands are overexpressed in various human cancers, including colorectal malignancies, suggesting important roles in many aspects of cancer development and progression as well as in cellular repulsive responses. The ectodomain of EphB2 receptor is cleav...

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Detalles Bibliográficos
Autores principales: Okumura, Fumihiko, Joo-Okumura, Akiko, Obara, Keisuke, Petersen, Alexander, Nishikimi, Akihiko, Fukui, Yoshinori, Nakatsukasa, Kunio, Kamura, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683763/
https://www.ncbi.nlm.nih.gov/pubmed/28931592
http://dx.doi.org/10.1091/mbc.E17-07-0450