Cargando…
Retromer stops beta-arrestin 1–mediated signaling from internalized cannabinoid 2 receptors
G protein–coupled receptors mediate their complex functions through activation of signaling cascades from receptors localized at the cell surface and endosomal compartments. These signaling pathways are modulated by heterotrimeric G proteins and the scaffold proteins beta-arrestin 1 and 2. However,...
Autores principales: | Nogueras-Ortiz, Carlos, Roman-Vendrell, Cristina, Mateo-Semidey, Gabriel E., Liao, Yu-Hsien, Kendall, Debra A., Yudowski, Guillermo A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683765/ https://www.ncbi.nlm.nih.gov/pubmed/28954865 http://dx.doi.org/10.1091/mbc.E17-03-0198 |
Ejemplares similares
-
Mechanisms of Biased β-Arrestin-Mediated Signaling Downstream from the Cannabinoid 1 Receptor
por: Delgado-Peraza, Francheska, et al.
Publicado: (2016) -
Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease
por: Kendall, Debra A., et al.
Publicado: (2017) -
Ligand-specific endocytic dwell times control functional selectivity of the
cannabinoid receptor 1
por: Flores-Otero, Jacqueline, et al.
Publicado: (2014) -
Cannabinoid 1 (CB(1)) receptor arrestin subtype‐selectivity and phosphorylation dependence
por: Manning, Jamie J., et al.
Publicado: (2022) -
Retromer revisited: Evolving roles for retromer in endosomal sorting
por: Chamberland, John P., et al.
Publicado: (2017)