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Retromer stops beta-arrestin 1–mediated signaling from internalized cannabinoid 2 receptors

G protein–coupled receptors mediate their complex functions through activation of signaling cascades from receptors localized at the cell surface and endosomal compartments. These signaling pathways are modulated by heterotrimeric G proteins and the scaffold proteins beta-arrestin 1 and 2. However,...

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Detalles Bibliográficos
Autores principales: Nogueras-Ortiz, Carlos, Roman-Vendrell, Cristina, Mateo-Semidey, Gabriel E., Liao, Yu-Hsien, Kendall, Debra A., Yudowski, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683765/
https://www.ncbi.nlm.nih.gov/pubmed/28954865
http://dx.doi.org/10.1091/mbc.E17-03-0198