Novel cationic lipid nanoparticles as an ophthalmic delivery system for multicomponent drugs: development, characterization, in vitro permeation, in vivo pharmacokinetic, and molecular dynamics studies

The purpose of this study was to prepare, optimize, and characterize a cationic lipid nanoparticle (CLN) system containing multicomponent drugs using a molecular dynamics model as a novel method of evaluating formulations. Puerarin (PUE) and scutellarin (SCU) were used as model drugs. CLNs were succ...

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Detalles Bibliográficos
Autores principales: Wang, Jialu, Zhao, Fang, Liu, Rui, Chen, Jingjing, Zhang, Qinghua, Lao, Ruijuan, Wang, Ze, Jin, Xin, Liu, Changxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683773/
https://www.ncbi.nlm.nih.gov/pubmed/29158673
http://dx.doi.org/10.2147/IJN.S139436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683773/
https://www.ncbi.nlm.nih.gov/pubmed/29158673
http://dx.doi.org/10.2147/IJN.S139436

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