A comparative pharmacokinetic and tolerability analysis of the novel orotic acid salt form of tenofovir disoproxil and the fumaric acid salt form in healthy subjects

A novel orotic acid salt form of tenofovir disoproxil (DA-2802) was developed and is expected to replace the fumaric acid salt form. The pharmacokinetic (PK) characteristics and tolerability profiles of DA-2802 were compared to those of tenofovir disoproxil fumarate (TDF, Viread(®)) in healthy subje...

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Detalles Bibliográficos
Autores principales: Kim, Yu Kyong, Choi, Mun Ju, Oh, Tae Young, Yu, Kyung-Sang, Lee, SeungHwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683794/
https://www.ncbi.nlm.nih.gov/pubmed/29158663
http://dx.doi.org/10.2147/DDDT.S149125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683794/
https://www.ncbi.nlm.nih.gov/pubmed/29158663
http://dx.doi.org/10.2147/DDDT.S149125

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