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Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals

The biological mechanisms that link Beta-amyloid (Aβ) plaque deposition, neurodegeneration, and clinical decline in Alzheimer's disease (AD) dementia, have not been completely elucidated. Here we studied whether amyloid accumulation and neurodegeneration, independently or interactively, predict...

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Detalles Bibliográficos
Autores principales: d'Oleire Uquillas, Federico, Jacobs, Heidi I.L., Hanseeuw, Bernard, Marshall, Gad A., Properzi, Michael, Schultz, Aaron P., LaPoint, Molly R., Johnson, Keith A., Sperling, Reisa A., Vannini, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683806/
https://www.ncbi.nlm.nih.gov/pubmed/29159051
http://dx.doi.org/10.1016/j.nicl.2017.10.034