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Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals
The biological mechanisms that link Beta-amyloid (Aβ) plaque deposition, neurodegeneration, and clinical decline in Alzheimer's disease (AD) dementia, have not been completely elucidated. Here we studied whether amyloid accumulation and neurodegeneration, independently or interactively, predict...
Autores principales: | d'Oleire Uquillas, Federico, Jacobs, Heidi I.L., Hanseeuw, Bernard, Marshall, Gad A., Properzi, Michael, Schultz, Aaron P., LaPoint, Molly R., Johnson, Keith A., Sperling, Reisa A., Vannini, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683806/ https://www.ncbi.nlm.nih.gov/pubmed/29159051 http://dx.doi.org/10.1016/j.nicl.2017.10.034 |
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