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Rescuing p53 from mdm2 by a pre-structured motif in intrinsically unfolded SUMO specific protease 4
Many intrinsically unstructured/unfolded proteins (IUPs) contain transient local secondary structures even though they are “unstructured” in a tertiary sense. These local secondary structures are named “pre-structured motifs (PreSMos)” and in fact are the specificity determinants for IUP-target bind...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683816/ https://www.ncbi.nlm.nih.gov/pubmed/28712389 http://dx.doi.org/10.5483/BMBRep.2017.50.10.131 |