Rescuing p53 from mdm2 by a pre-structured motif in intrinsically unfolded SUMO specific protease 4

Many intrinsically unstructured/unfolded proteins (IUPs) contain transient local secondary structures even though they are “unstructured” in a tertiary sense. These local secondary structures are named “pre-structured motifs (PreSMos)” and in fact are the specificity determinants for IUP-target bind...

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Detalles Bibliográficos
Autores principales: Kim, Do-Hyoung, Lee, Chewook, Kim, Bom, Lee, Si-Hyung, Han, Kyou-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683816/
https://www.ncbi.nlm.nih.gov/pubmed/28712389
http://dx.doi.org/10.5483/BMBRep.2017.50.10.131

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