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An NMR study on the intrinsically disordered core transactivation domain of human glucocorticoid receptor

A large number of transcriptional activation domains (TADs) are intrinsically unstructured, meaning they are devoid of a three-dimensional structure. The fact that these TADs are transcriptionally active without forming a 3-D structure raises the question of what features in these domains enable the...

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Detalles Bibliográficos
Autores principales: Kim, Do-Hyoung, Wright, Anthony, Han, Kyou-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683822/
https://www.ncbi.nlm.nih.gov/pubmed/28946939
http://dx.doi.org/10.5483/BMBRep.2017.50.10.152