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Canonical Stimulation of the NLRP3 Inflammasome by Fungal Antigens Links Innate and Adaptive B-Lymphocyte Responses by Modulating IL-1β and IgM Production

The NLRP3 inflammasome is activated in response to different bacterial, viral, and fungal pathogens and serves as modulator of different pattern recognition receptors signaling pathways. One of the main functions of NLRP3 is to participate in IL-1β maturation which is important in the host defense a...

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Detalles Bibliográficos
Autores principales: Ali, Mohamed F., Dasari, Harika, Van Keulen, Virginia P., Carmona, Eva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684107/
https://www.ncbi.nlm.nih.gov/pubmed/29170665
http://dx.doi.org/10.3389/fimmu.2017.01504