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Will a mAb-Based Immunotherapy Directed against Cancer Stem Cells Be Feasible?

The cancer stem cell (CSC) hypothesis suggests that within a tumor, there is a small subpopulation of cells with stem cell properties responsible for tumor maintenance and metastasis generation. This hypothesis also implies that new antitumor drugs, rather than targeting the bulk of the tumor mass,...

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Detalles Bibliográficos
Autores principales: Santamaria, Silvia, Delgado, Marisa, Kremer, Leonor, Garcia-Sanz, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684111/
https://www.ncbi.nlm.nih.gov/pubmed/29170667
http://dx.doi.org/10.3389/fimmu.2017.01509