Shedding of Microvesicles from Microglia Contributes to the Effects Induced by Metabotropic Glutamate Receptor 5 Activation on Neuronal Death

Metabotropic glutamate (mGlu) receptor 5 is involved in neuroinflammation and has been shown to mediate reduced inflammation and neurotoxicity and to modify microglia polarization. On the other hand, blockade of mGlu5 receptor results in inhibition of microglia activation. To dissect this controvers...

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Detalles Bibliográficos
Autores principales: Beneventano, Martina, Spampinato, Simona F., Merlo, Sara, Chisari, Mariangela, Platania, Paola, Ragusa, Marco, Purrello, Michele, Nicoletti, Ferdinando, Sortino, Maria Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684115/
https://www.ncbi.nlm.nih.gov/pubmed/29170640
http://dx.doi.org/10.3389/fphar.2017.00812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684115/
https://www.ncbi.nlm.nih.gov/pubmed/29170640
http://dx.doi.org/10.3389/fphar.2017.00812

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