A Novel Strategy to Predict Carcinogenicity of Antiparasitics Based on a Combination of DNA Lesions and Bacterial Mutagenicity Tests

Genotoxicity and carcinogenicity testing of pharmaceuticals prior to commercialization is requested by regulatory agencies. The bacterial mutagenicity test was considered having the highest accuracy of carcinogenic prediction. However, some evidences suggest that it always results in false-positive...

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Detalles Bibliográficos
Autores principales: Liu, Qianying, Lei, Zhixin, Zhu, Feng, Ihsan, Awais, Wang, Xu, Yuan, Zonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684118/
https://www.ncbi.nlm.nih.gov/pubmed/29170735
http://dx.doi.org/10.3389/fpubh.2017.00288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684118/
https://www.ncbi.nlm.nih.gov/pubmed/29170735
http://dx.doi.org/10.3389/fpubh.2017.00288

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