PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development

The precise molecular mechanism underlying the regulation of early B cell lymphopoiesis is unclear. The PLCγ signaling pathway is critical for antigen receptor-mediated lymphocyte activation, but its function in cytokine signaling is unknown. Here we show that PLCγ1/PLCγ2 double deficiency in mice b...

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Detalles Bibliográficos
Autores principales: Yu, Mei, Chen, Yuhong, Zeng, Hu, Zheng, Yongwei, Fu, Guoping, Zhu, Wen, Broeckel, Ulrich, Aggarwal, Praful, Turner, Amy, Neale, Geoffrey, Guy, Cliff, Zhu, Nan, Chi, Hongbo, Wen, Renren, Wang, Demin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684131/
https://www.ncbi.nlm.nih.gov/pubmed/29133930
http://dx.doi.org/10.1038/s41467-017-01388-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684131/
https://www.ncbi.nlm.nih.gov/pubmed/29133930
http://dx.doi.org/10.1038/s41467-017-01388-5

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