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Exploration of Antifungal and Immunomodulatory Potentials of a Furanone Derivative to Rescue Disseminated Cryptococosis in Mice

Cryptococcus neoformans infection is quite complex with both host-pathogen interaction and host immune profile determining disease progress and therapeutic outcome. Hence in the present study, the potential utility of (E)-5-benzylidenedihydrofuran-2(3 H)-one (compound-6) was explored as an effective...

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Detalles Bibliográficos
Autores principales: Rathore, Sudarshan Singh, Isravel, Muthukrishnan, Vellaisamy, Sridharan, Chellappan, David Raj, Cheepurupalli, Lalitha, Raman, Thiagarajan, Ramakrishnan, Jayapradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684196/
https://www.ncbi.nlm.nih.gov/pubmed/29133871
http://dx.doi.org/10.1038/s41598-017-15500-8