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LC-MS guided isolation of three pairs of enantiomeric alkaloids from Macleaya cordata and their enantioseparations, antiproliferative activity, apoptosis-inducing property

(±)-Macleayins F–H (1–3), three pairs of new enantiomeric alkaloid dimers, along with four known alkaloids (4–7) as their plausible biogenetic precursors, were isolated from the aerial parts of Macleaya cordata. Compounds 1–3 were obtained under the guidance of LC-MS investigation, and their structu...

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Detalles Bibliográficos
Autores principales: Sai, Chunmei, Li, Dahong, Li, Shengge, Han, Tong, Guo, Yongzhi, Li, Zhanlin, Hua, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684219/
https://www.ncbi.nlm.nih.gov/pubmed/29133815
http://dx.doi.org/10.1038/s41598-017-15423-4