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Serotonin regulates prostate growth through androgen receptor modulation

Aging and testosterone almost inexorably cause benign prostatic hyperplasia (BPH) in Human males. However, etiology of BPH is largely unknown. Serotonin (5-HT) is produced by neuroendocrine prostatic cells and presents in high concentration in normal prostatic transition zone, but its function in pr...

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Detalles Bibliográficos
Autores principales: Carvalho-Dias, Emanuel, Miranda, Alice, Martinho, Olga, Mota, Paulo, Costa, Ângela, Nogueira-Silva, Cristina, Moura, Rute S., Alenina, Natalia, Bader, Michael, Autorino, Riccardo, Lima, Estêvão, Correia-Pinto, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684231/
https://www.ncbi.nlm.nih.gov/pubmed/29133842
http://dx.doi.org/10.1038/s41598-017-15832-5