A conformational switch in initiation factor 2 controls the fidelity of translation initiation in bacteria

Initiation factor (IF) 2 controls the fidelity of translation initiation by selectively increasing the rate of 50S ribosomal subunit joining to 30S initiation complexes (ICs) that carry an N-formyl-methionyl-tRNA (fMet-tRNA(fMet)). Previous studies suggest that rapid 50S subunit joining involves a G...

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Detalles Bibliográficos
Autores principales: Caban, Kelvin, Pavlov, Michael, Ehrenberg, Måns, Gonzalez, Ruben L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684235/
https://www.ncbi.nlm.nih.gov/pubmed/29133802
http://dx.doi.org/10.1038/s41467-017-01492-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684235/
https://www.ncbi.nlm.nih.gov/pubmed/29133802
http://dx.doi.org/10.1038/s41467-017-01492-6

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