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Longrange PCR-based next-generation sequencing in pharmacokinetics and pharmacodynamics study of propofol among patients under general anaesthesia

The individual response of patients to propofol results from the influence of genetic factors. However, the state of knowledge in this matter still remains insufficient. The aim of our study was to determine genetic predictors of variable pharmacokinetics and pharmacodynamics of propofol within sele...

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Detalles Bibliográficos
Autores principales: Zakerska-Banaszak, Oliwia, Skrzypczak-Zielinska, Marzena, Tamowicz, Barbara, Mikstacki, Adam, Walczak, Michal, Prendecki, Michal, Dorszewska, Jolanta, Pollak, Agnieszka, Lechowicz, Urszula, Oldak, Monika, Huminska-Lisowska, Kinga, Molinska-Glura, Marta, Szalata, Marlena, Slomski, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684313/
https://www.ncbi.nlm.nih.gov/pubmed/29133890
http://dx.doi.org/10.1038/s41598-017-15657-2