Random protein sequences can form defined secondary structures and are well-tolerated in vivo

The protein sequences found in nature represent a tiny fraction of the potential sequences that could be constructed from the 20-amino-acid alphabet. To help define the properties that shaped proteins to stand out from the space of possible alternatives, we conducted a systematic computational and e...

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Detalles Bibliográficos
Autores principales: Tretyachenko, Vyacheslav, Vymětal, Jiří, Bednárová, Lucie, Kopecký, Vladimír, Hofbauerová, Kateřina, Jindrová, Helena, Hubálek, Martin, Souček, Radko, Konvalinka, Jan, Vondrášek, Jiří, Hlouchová, Klára
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684393/
https://www.ncbi.nlm.nih.gov/pubmed/29133927
http://dx.doi.org/10.1038/s41598-017-15635-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684393/
https://www.ncbi.nlm.nih.gov/pubmed/29133927
http://dx.doi.org/10.1038/s41598-017-15635-8

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