A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses

Compelling data in the literature from the recent years leave no doubt about the pluridimensional nature of G protein-coupled receptor function and the fact that some ligands can couple with different efficacies to the multiple pathways that a receptor can signal through, a phenomenon most commonly...

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Detalles Bibliográficos
Autores principales: Burgueño, Javier, Pujol, Marta, Monroy, Xavier, Roche, David, Varela, Maria Jose, Merlos, Manuel, Giraldo, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684405/
https://www.ncbi.nlm.nih.gov/pubmed/29133887
http://dx.doi.org/10.1038/s41598-017-15258-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684405/
https://www.ncbi.nlm.nih.gov/pubmed/29133887
http://dx.doi.org/10.1038/s41598-017-15258-z

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