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A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses
Compelling data in the literature from the recent years leave no doubt about the pluridimensional nature of G protein-coupled receptor function and the fact that some ligands can couple with different efficacies to the multiple pathways that a receptor can signal through, a phenomenon most commonly...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684405/ https://www.ncbi.nlm.nih.gov/pubmed/29133887 http://dx.doi.org/10.1038/s41598-017-15258-z |