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Apelin conformational and binding equilibria upon micelle interaction primarily depend on membrane-mimetic headgroup
Apelin is one of two peptide hormones that activate the apelin receptor (AR or APJ) to regulate the cardiovascular system, central nervous system, and adipoinsular axis. Here, we apply circular dichroism (CD) spectropolarimetry and nuclear magnetic resonance (NMR) spectroscopy to characterize the po...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684411/ https://www.ncbi.nlm.nih.gov/pubmed/29133807 http://dx.doi.org/10.1038/s41598-017-14784-0 |