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Therapeutic targeting of extracellular DNA improves the outcome of intestinal ischemic reperfusion injury in neonatal rats

Thrombosis and inflammation cooperate in the development of intestinal infarction. Recent studies suggest that extracellular DNA released by damaged cells or neutrophils in form of extracellular traps (NETs) contributes to organ damage in experimental models of ischemia-reperfusion injury. Here we c...

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Detalles Bibliográficos
Autores principales: Boettcher, Michael, Eschenburg, Georg, Mietzsch, Stefan, Jiménez-Alcázar, Miguel, Klinke, Michaela, Vincent, Deirdre, Tiemann, Bastian, Bergholz, Robert, Reinshagen, Konrad, Fuchs, Tobias A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684414/
https://www.ncbi.nlm.nih.gov/pubmed/29133856
http://dx.doi.org/10.1038/s41598-017-15807-6