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Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species

Antimicrobial peptides as part of the mammalian innate immune system target and remove major bacterial pathogens, often through irreversible damage of their cellular membranes. To explore the mechanism by which the important cathelicidin peptide LL-37 of the human innate immune system interacts with...

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Detalles Bibliográficos
Autores principales: Sancho-Vaello, Enea, François, Patrice, Bonetti, Eve-Julie, Lilie, Hauke, Finger, Sebastian, Gil-Ortiz, Fernando, Gil-Carton, David, Zeth, Kornelius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684418/
https://www.ncbi.nlm.nih.gov/pubmed/29133814
http://dx.doi.org/10.1038/s41598-017-14206-1