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Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease

The relationships between β-amyloid (Aβ), tau and neurodegeneration within Alzheimer's Disease pathogenesis are not fully understood. To explore these associations in vivo, we evaluated 30 Aβ PET-positive patients (mean ± sd age 62.4 ± 8.3) with mild probable AD and 12 Aβ PET-negative healthy c...

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Detalles Bibliográficos
Autores principales: Iaccarino, Leonardo, Tammewar, Gautam, Ayakta, Nagehan, Baker, Suzanne L., Bejanin, Alexandre, Boxer, Adam L., Gorno-Tempini, Maria Luisa, Janabi, Mustafa, Kramer, Joel H., Lazaris, Andreas, Lockhart, Samuel N., Miller, Bruce L., Miller, Zachary A., O'Neil, James P., Ossenkoppele, Rik, Rosen, Howard J., Schonhaut, Daniel R., Jagust, William J., Rabinovici, Gil D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684433/
https://www.ncbi.nlm.nih.gov/pubmed/29159058
http://dx.doi.org/10.1016/j.nicl.2017.09.016