Cargando…

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion

Carbonic anhydrase IX (CAIX) is a hypoxia inducible factor 1-induced, cell surface pH regulating enzyme with an established role in tumor progression and clinical outcome. However, the molecular basis of CAIX-mediated tumor progression remains unclear. Here, we have utilized proximity dependent biot...

Descripción completa

Detalles Bibliográficos
Autores principales: Swayampakula, M, McDonald, P C, Vallejo, M, Coyaud, E, Chafe, S C, Westerback, A, Venkateswaran, G, Shankar, J, Gao, G, Laurent, E M N, Lou, Y, Bennewith, K L, Supuran, C T, Nabi, I R, Raught, B, Dedhar, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684442/
https://www.ncbi.nlm.nih.gov/pubmed/28692057
http://dx.doi.org/10.1038/onc.2017.219