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The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion
Carbonic anhydrase IX (CAIX) is a hypoxia inducible factor 1-induced, cell surface pH regulating enzyme with an established role in tumor progression and clinical outcome. However, the molecular basis of CAIX-mediated tumor progression remains unclear. Here, we have utilized proximity dependent biot...
Autores principales: | Swayampakula, M, McDonald, P C, Vallejo, M, Coyaud, E, Chafe, S C, Westerback, A, Venkateswaran, G, Shankar, J, Gao, G, Laurent, E M N, Lou, Y, Bennewith, K L, Supuran, C T, Nabi, I R, Raught, B, Dedhar, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684442/ https://www.ncbi.nlm.nih.gov/pubmed/28692057 http://dx.doi.org/10.1038/onc.2017.219 |
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