Cargando…

Inhibition of Murine Cytomegalovirus Infection in Animals by RNase P-Associated External Guide Sequences

External guide sequence (EGS) RNAs are associated with ribonuclease P (RNase P), a tRNA processing enzyme, and represent promising agents for gene-targeting applications as they can direct RNase-P-mediated cleavage of a target mRNA. Using murine cytomegalovirus (MCMV) as a model system, we examined...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wei, Sheng, Jingxue, Xu, Mengqiong, Vu, Gia-Phong, Yang, Zhu, Liu, Yujun, Sun, Xu, Trang, Phong, Lu, Sangwei, Liu, Fenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684469/
https://www.ncbi.nlm.nih.gov/pubmed/29246310
http://dx.doi.org/10.1016/j.omtn.2017.10.007