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Inhibition of Murine Cytomegalovirus Infection in Animals by RNase P-Associated External Guide Sequences
External guide sequence (EGS) RNAs are associated with ribonuclease P (RNase P), a tRNA processing enzyme, and represent promising agents for gene-targeting applications as they can direct RNase-P-mediated cleavage of a target mRNA. Using murine cytomegalovirus (MCMV) as a model system, we examined...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684469/ https://www.ncbi.nlm.nih.gov/pubmed/29246310 http://dx.doi.org/10.1016/j.omtn.2017.10.007 |