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Heparanase Inhibition Reduces Glucose Levels, Blood Pressure, and Oxidative Stress in Apolipoprotein E Knockout Mice

BACKGROUND: Atherosclerosis is a multifactorial process. Emerging evidence highlights a role of the enzyme heparanase in various disease states, including atherosclerosis formation and progression. OBJECTIVE: The aim of the study was to investigate the effect of heparanase inhibition on blood pressu...

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Detalles Bibliográficos
Autores principales: Hamoud, Shadi, Shekh Muhammad, Rabia, Abu-Saleh, Niroz, Hassan, Ahmad, Zohar, Yaniv, Hayek, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684525/
https://www.ncbi.nlm.nih.gov/pubmed/29226146
http://dx.doi.org/10.1155/2017/7357495