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Heparanase Inhibition Reduces Glucose Levels, Blood Pressure, and Oxidative Stress in Apolipoprotein E Knockout Mice
BACKGROUND: Atherosclerosis is a multifactorial process. Emerging evidence highlights a role of the enzyme heparanase in various disease states, including atherosclerosis formation and progression. OBJECTIVE: The aim of the study was to investigate the effect of heparanase inhibition on blood pressu...
Autores principales: | Hamoud, Shadi, Shekh Muhammad, Rabia, Abu-Saleh, Niroz, Hassan, Ahmad, Zohar, Yaniv, Hayek, Tony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684525/ https://www.ncbi.nlm.nih.gov/pubmed/29226146 http://dx.doi.org/10.1155/2017/7357495 |
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