Impaired mitochondrial calcium uptake caused by tacrolimus underlies beta-cell failure

BACKGROUND: One of the most common side effects of the immunosuppressive drug tacrolimus (FK506) is the increased risk of new-onset diabetes mellitus. However, the molecular mechanisms underlying this association have not been fully clarified. METHODS: We studied the effects of the therapeutic dose...

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Detalles Bibliográficos
Autores principales: Lombardi, Angela, Trimarco, Bruno, Iaccarino, Guido, Santulli, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684747/
https://www.ncbi.nlm.nih.gov/pubmed/29132395
http://dx.doi.org/10.1186/s12964-017-0203-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684747/
https://www.ncbi.nlm.nih.gov/pubmed/29132395
http://dx.doi.org/10.1186/s12964-017-0203-0

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