Chronic administration of parecoxib exerts anxiolytic-like and memory enhancing effects and modulates synaptophysin expression in mice

BACKGROUND: Previous studies have shown that cyclooxygenase-2, a key enzyme that converts arachidonic acid to prostaglandins, is involved in anxiety and cognitive processes, but few studies have investigated the effects of chronic administration of cyclooxygenase-2 inhibitors on anxiety, learning an...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Jin, Xin, Kuang, Xin, Tian, Shaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684753/
https://www.ncbi.nlm.nih.gov/pubmed/29132299
http://dx.doi.org/10.1186/s12871-017-0443-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684753/
https://www.ncbi.nlm.nih.gov/pubmed/29132299
http://dx.doi.org/10.1186/s12871-017-0443-y

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