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Effect of efflux pump inhibitors on the susceptibility of Mycobacterium tuberculosis to isoniazid

BACKGROUND: Mycobacterium can develop drug resistance (DR) by mutation of its existing gene. However, the existence of DR without mutation shows the need to look for an alternative mechanism such as the role of efflux pumps. In this study, we examined the effect of efflux pump inhibitors on isoniazi...

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Detalles Bibliográficos
Autores principales: Jaiswal, Indu, Jain, Amita, Verma, Sanjeev Kumar, Singh, Pooja, Kant, Surya, Singh, Mastan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684805/
https://www.ncbi.nlm.nih.gov/pubmed/29098993
http://dx.doi.org/10.4103/0970-2113.217567