An environmental pollutant, 9,10‐phenanthrenequinone, activates human TRPA1 via critical cysteines 621 and 665

Transient receptor potential ankyrin 1 (TRPA1) is activated by noxious cold, mechanical stimulation, and irritant chemicals. In our recent study, 9, 10‐phenanthrenequinone (9,10‐PQ) is the most potent irritant for activation of NRF2 among 1395 cigarette smoke components and it may be, therefore, imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Muraki, Katsuhiko, Sekine, Takashi, Ando, Yuna, Suzuki, Hiroka, Hatano, Noriyuki, Hirata, Tadashi, Muraki, Yukiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684862/
https://www.ncbi.nlm.nih.gov/pubmed/28805980
http://dx.doi.org/10.1002/prp2.342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684862/
https://www.ncbi.nlm.nih.gov/pubmed/28805980
http://dx.doi.org/10.1002/prp2.342

Ejemplares similares