Cargando…

Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B cells from apoptosis, enhance their migration and induce gene expression modifications

Interactions between chronic lymphocytic leukemia (CLL) B cells and the bone marrow (BM) microenvironment play a major function in the physiopathology of CLL. Extracellular vesicles (EVs), which are composed of exosomes and microparticles, play an important role in cell communication. However, littl...

Descripción completa

Detalles Bibliográficos
Autores principales: Crompot, Emerence, Van Damme, Michael, Pieters, Karlien, Vermeersch, Marjorie, Perez-Morga, David, Mineur, Philippe, Maerevoet, Marie, Meuleman, Nathalie, Bron, Dominique, Lagneaux, Laurence, Stamatopoulos, Basile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685228/
https://www.ncbi.nlm.nih.gov/pubmed/28596280
http://dx.doi.org/10.3324/haematol.2016.163337