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Tanshinone IIA Protects Endothelial Cells from H(2)O(2)-Induced Injuries via PXR Activation

Tanshinone IIA (Tan IIA) is a pharmacologically active substance extracted from the rhizome of Salvia miltiorrhiza Bunge (also known as the Chinese herb Danshen), and is widely used to treat atherosclerosis. The pregnane X receptor (PXR) is a nuclear receptor that is a key regulator of xenobiotic an...

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Detalles Bibliográficos
Autores principales: Zhu, Haiyan, Chen, Zhiwu, Ma, Zengchun, Tan, Hongling, Xiao, Chengrong, Tang, Xianglin, Zhang, Boli, Wang, Yuguang, Gao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685429/
https://www.ncbi.nlm.nih.gov/pubmed/28173640
http://dx.doi.org/10.4062/biomolther.2016.179