Induction of Cell Death by Betulinic Acid through Induction of Apoptosis and Inhibition of Autophagic Flux in Microglia BV-2 Cells

Betulinic acid (BA), a natural pentacyclic triterpene found in many medicinal plants is known to have various biological activity including tumor suppression and anti-inflammatory effects. In this study, the cell-death induction effect of BA was investigated in BV-2 microglia cells. BA was cytotoxic...

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Detalles Bibliográficos
Autores principales: Seo, Jeongbin, Jung, Juneyoung, Jang, Dae Sik, Kim, Joungmok, Kim, Jeong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685431/
https://www.ncbi.nlm.nih.gov/pubmed/28274097
http://dx.doi.org/10.4062/biomolther.2016.255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685431/
https://www.ncbi.nlm.nih.gov/pubmed/28274097
http://dx.doi.org/10.4062/biomolther.2016.255

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